The citizens start to question why the town is still under a quarantine that has cut off medical and building supplies. The citizens find themselves on the verge of a major medical pandemic. Russell and Sheriff Underlay must track down the source of this quickly spreading virus.

Larkin barely survives a car crash and the fate of her unborn baby is unknown. Larkin gets picked up by a stranger in a pick-up but she soon becomes suspicious of his motives. Meanwhile, Mariel tries to reconnect with Jesse.

After a couple reads his blogs, they abduct Dave to find out what he knows about the hurricane's aftermath. Underlay and Sirk discover the identity of the woman in the bay and Sirk gets a glimpse of the orange lights.

Russell and Tom team together to try to catch a pregnant Christina and Derek, who are armed, dangerous and on the run. While searching Russell and Tom find a group of migrant workers. Mariel confides in Jesse and Rose about what happened to her. An unconscious Kira is in the hospital after her encounter with the orange being. Larkin searches for more answers about Paxton and his real reason for being in the area during the hurricane.

Russell and Underlay find that they have to work together as another storm is quickly approaching. They need to get their families out of Homestead and to try to find where Szura has stashed away the hybrids.