While on assignment, agent Michael Westen gets a "Burn Notice" and becomes untouchable. Having no idea what or who triggered his demise, Michael returns to his hometown, Miami, determined to find out the reason for his sudden termination.

Michael helps Madeline's friend retrieve money from a swindler, and in return he receives information about some visitors that came to his mother's home.

Michael works to rid a community in little Havana of a crime boss, all the while baiting Jason Bly at the risk of his family and friends.

Michael is hired to track down a woman's estranged husband, who has disappeared with their son. Michael soon finds himself pitted against somebody just as skilled and dangerous as he is.

Sam takes on a case for a woman named Gillian, who is being blackmailed into using her security clearance to help smuggle heroin into the United States. Meanwhile, Michael is busy trying to arrange a meeting with Philip Cowan.

Michael must rescue Sam from heroin smugglers, who happen to be ex-Special Forces, while also evading agents who are out to get him.

Having been recruited by the people who burned him, Michael's new handler, Carla, tasks him with helping a computer tech, whose wife and daughter were kidnapped, liberate some information that is guarded by mercenaries.

When someone's suspected of embezzling from a hip-hop mogul's charity, Michael attempts to trick the thief into stealing a larger sum.

Michael prevents a man from committing suicide, whose son suffers from a heart condition. He had lost his savings in a scam after investing in a "miracle drug" for his son, so Michael decides to get him his money back.

Meanwhile, he has to deal with an explosion at his place and his brother in jail.

Michael gets to know Victor's motivation and his connection to Carla after capturing him. When the truth about Carla's organization is revealed, everyone is put in danger.

Michael is bailed out of jail by an old friend who asks for his help in return.

When a recently widowed woman hires Michael and Fiona to get her away from a group of violent con men, Michael turns to Madeline for help — but he may ask her to go too far. Meanwhile, a mysterious contact goes to extreme lengths to get Michael's attention.

International fugitive Simon is loose and Michael's on the run from the FBI for his role in Simon’s escape. When Simon confronts Michael and threatens to blow up a Miami Beach hotel, Michael must call on his friends and an old enemy to help him avoid disaster and put Simon back in the dark hole where he belongs.

Michael helps Fiona and Sam protect a lawyer against the city's most dangerous biker gang. Meanwhile, he must team up with an unlikely ally to stop a looming terrorist threat... but quickly finds that no mission is without its price.

When dangerous mobsters threaten a port worker, Michael takes on the case. With Jesse, Michael also looks for intel on an underground-artillery operation.

Fiona attempts to find Jesse and convince him to meet with Michael. Meanwhile, Michael helps a criminal defense attorney rescue his daughter after she is kidnapped by one of his clients.

Michael, Fiona, and Jessie try to keep the NOC list away from Vaughn and his strike team. Meanwhile Sam and Madeline try to convince Congressman Cowley to pass the list higher up.

Michael works with his old agency to go after the people who burned him in a case that leads the group to Venezuela.

Michael and Fiona plan to abduct a hacker in Puerto Rico in order to obtain his software, but the man has several other enemies to contend with. Elsewhere, Madeline learns to retrieve information from the police under the tutelage of Sam and Jesse.

As the team reaches a breaking point with Anson and his sinister plans, Pearce puts Michael in charge of his biggest CIA mission yet.

Michael pursues Anson in Miami. Meanwhile, Fiona is taken into custody and interrogated by a former foe.

Series Finale. Michael must regain the trust of those closest to him in order to finish what he started.