The doctors face one of their toughest cases ever when a patient that has been attacked by a mountain lion comes to the E.R. with the most severe injuries that the doctors have ever encountered. Meanwhile, one woman complains of being dizzy but ends up actually being high. Also, a young girl is stuck by thousands of needles after rolling down the side of a cliff.

A man is shot through the heart while his store is being robbed.

A man's religion prohibits him from getting treatment for a rattlesnake bite, so ER doctors struggle to find a way to help him.

When an 11-year-old comes down with a severe ailment that has a track record of killing almost all of its victims, the doctors are forced to try an untested treatment.

After a tornado strikes Oklahoma, a woman comes to the E.R. with a fence picket impaled through her head.

The E.R. doctors have to reattach a 7-year-old boy's arm after he is involved in a truck accident. Meanwhile, a teenage boy comes to the hospital unable to move his ankles and feet. Also, a man has a serious skin rash that is stumping the doctors and collapsing his lungs.

A young boy is rushed to the emergency room immediately after a football game.

A skier runs into bad luck after hitting a tree at 50 miles per hour when his blood will not clot and the power goes out at the emergency room.

A boy that has been crushed under a heavy stack of drywall is brought in with a possibilty of multiple organ failure.

A woman on the way to her own wedding has a car accident and is sent to the ER with severe facial injuries. Meanwhile, a prisoner comes to the ER, but the doctors are wary of him.

A drunken cowboy ends up in the ER while a patient with a gunshot wound in the thigh complains of chest pains.

A young boy is brought in that has been ejected from a car during an accident and he doesn't look good at all.

Doctors must fight to save an injured police officer's legs. While this happens, a royal prinncess has a hangover and a boy gets a blood clot and could die.

A snakebite specialist finds it difficult to treat his own son. Also, a young boy who broke his leg was drugged up with weed and a golfer got a golf club through his head.

A 15-year-old boy suffers a severe head injury that he got while playing baseball. Meanwhile, a doctor tries to help a patient claiming to have bugs crawling inside of her scalp.

A very unexpected gunman takes hostages and guns down the ER.

A trauma surgeon attempts removing a four pound hook from a construction worker's skull without putting his life in any more danger.