An ER doctor must solve why a student is having difficulty breathing, and what his fraternity brothers might be hiding; a man falls off a roof and is impaled by a shovel; a police officer has a heart attack that endangers the hospital staff.

A college student's head is impaled by a trophy deer's antlers; a car crash victim leads the doctor to believe her baby may still be at the accident scene; a nurse's ex-boyfriend brings his new girlfriend to the ER and the nurse must help save her life.

A Halloween zombie with a problem below the belt mystifies doctors; when two unconscious men are involved in an accident, a doctor helps police determine which one was the carjacker; a doctor makes a mistake that amazingly explains a patient's condition.

A woman risks losing her finger after trying on an ill-fitting engagement ring; a body builder can't breathe and doctors are shocked to discover why; a doctor takes a break outside and is nearly struck by a car driven by her next patient.

A pianist's finger is accidentally sawed off and missing until his wife and dog come to the ER; a man's pacemaker is killing him, yet keeping him alive; and after his bachelor party, a nurse's fiancé is behaving bizarrely and needs urgent medical care.

A man injured in a medieval role-playing battle has a sword impaled in his head; a critically ill patient is so afraid of germs he won't allow doctors to treat him; two patients with the same life-threatening symptoms arrive separately from a fashion show.

A woman's face-lift goes terribly wrong; a hospital chaplain's sudden personality change baffles the ER staff; a pregnant woman's life-threatening symptoms need urgent treatment but the doctor must convince others of the diagnosis he saw in her eyes.

A man's face and body suddenly double in size; an ER physician races to determine why a young woman is burning up from the inside out after a day at the beach; a grumpy old man nearly dies before revealing an emotional secret.

A doctor treats three gunshot victims who claim be innocent bystanders but the police want to know who shot who; on his first day on the job, a doctor must perform emergency brain surgery in the ER; a young bride-to-be suddenly slips into a diabetic coma.

A woman stops eating because she believes she is dead; a runner goes blind in one eye during a marathon and takes a detour to the ER; doctors are baffled by an ER tech's stroke-like symptoms, until someone he loves also becomes ill.

A pregnant woman is shot in the abdomen but refuses some testing and treatment jeopardizing her life and the baby's; a doctor is the victim of a car burglary and thinks her patient may be the culprit; a storm is preventing a patient's life-saving surgery.

A pregnant woman's leg pain turns out to be flesh-eating virus, threatening life and limb; a Desert Storm war veteran swallows razor blades on a dare; a bride-to-be spends her wedding day in the ER after collapsing at the altar.

Panicked moms-to-be and their anxious partners delivering far outside of their birth plans.

Doctors faced with extraordinary challenges and young lives hanging in the balance.

From the life-threatening to the light-hearted, nurses tell true medical stories from their unique perspectives.

Strange-but-true spooky cases that leave doctors proclaiming it must be a full moon.