With an entire town after the bounty on his head, Vash must contend with the dangerously destructive Nebraska Brothers - while saving the very same villagers who are bent on bringing him in!

Vash and Wolfwood enter a quick-draw competition in May City. If one of them wins, the prize money will go to a poor local family. Unfortunately, they’re both in line of fire - the contest is rigged!

Vash is thrown in jail after being accused of killing a local shoemaker. Even if he gets out of his cell, there’s going to be trouble -Monev the Gale is gunning for him after being hired by Legato!

The Roderick gang’s battle with Legato is violently interrupted by the fierce Gung-Ho Guns. Just as Vash begins to investigate the incident, he meets Dominique the Cyclops, a lethal beauty with an amazing power.

With reports of new Vash sightings, Meryl returns to the work of tracking him down. Meanwhile, Vash and Wolfwood make their way to a town where a family feud has escalated into a hostage situation.