Max Cassidy vanishes after leaving a message on his wife's voicemail, with both Jack and Ann frantic to find him. While investigating, Jack realises that Max was having an affair, and that he's gotten much deeper into a case than he should have following the murder of his partner, Jimmy, a man Max had felt was too green for undercover work. Both Jack and Ann fear the worst as the team tries to hunt down Max.

The team investigates when a young paramedic with gang ties disappears. Jack and Ann bond over their recent losses.

When Leah Robinson goes missing after a confrontation with a young man at an art gallery, the team mvoes in to investigate and soon become suspicious of Leah, suspecting her of murdering young women that she believed to be involved with her husband, Ken. Ann isn't quite ready to take her romance with Jack public, and their relationship gets rocky when their different methods of handling the case tip off the suspect.

The team searches for a teenage figure skater who disappears after practice one day and discover that many people in her life had reason to worry. The team's investigation leads to the rink's operator, a convicted rapist who was the last to see the girl.

After attorney Jennifer Nichols disappears, the team investigates the last few days in her life and soon find that she had grown disillusioned with her most recent relationship with Allen Davis. Discussions with a married ex-lover reveal that Nichols had recently gone through an old case file relating to a ten-year-old bank robbery, which has a connection to her recent relationship. Jack and Ann avoid discussing a recent development in their relationship -- her pregnancy.

Cindy Peterson, a mother who had become a stripper to support her family, goes missing after work one night, and Jack sends Elena in undercover at the strip club to learn what she can. Danny moves in to keep an eye on her after someone catches on to her spying, while Vivian discovers that Jim Peterson hasn't been completely honest with them. Jack faces censure from Olczyk over his relationship with Ann, and is angry with Ann after she admits to him that she thinks he let their relationship cloud his judgment in the Davis investigation.

Martin brings the team in on the hunt for a young woman that went missing after a priest attempted to exorcise a demon from her. He begins to feel guilty when he finds out he used to work with her, but doesn't remember her.

The team investigates the disappearance of social worker Eric Hayes, who had given thirty days notice to his job not long before. When their investigation leads them to a young pregnant woman who had already lost one child to the system, the agents begin to believe the disillusioned social worker may have been having an affair but soon discover that he may have been trying to right the wrong that drove him from his job. Danny has trouble with the investigation, as it reminds him of his own experience in foster care. Jack confides in Samantha about his relationship with Ann, but it may be too late.

When 17-year-old Ted Soros goes missing after a basketball game, the team begins an investigation, soon learning that Ted was an emancipated minor who was living on his own to attend a school with an exemplary basketball program. Learning he had recently contacted his mother with a request for legal advice from an uncle, the team begins to suspect that Ted may have done something that he could face criminal charges for, and realise that Ted's secret is connected to a university recruiting party. While the team works Ted's disappearance, Jack learns from Ann that she lost the baby, and waits for her at the clinic while she seeks medical attention.