After a confrontation with a local bully, foster teen William Hope disappears leaving his job at a burger restaurant late at night.

Chet Collins has been searching for his son since the boy was kidnapped four years earlier on a camping trip, and is the one case that Jack has never been able to forget. When Chet disappears, leaving behind only his wedding ring and the mountains of debt he had accumulated in his search, Jack will go to any lengths to find Collins and save him from himself.

The team investigate a disappearance of a flight attendant who may have been having a relationship with one of the pilot's.

The team find themselves up against the ropes as multiple mysteries arise in the case of a boxer. Dante Jones disappears moments before a bout with a $500,000 purse that which could have made him a title contender. Jack suspects it's stunt, but Vivian, a Jones fan, can't believe that the charity-loving, straight-arrow fighter would go doewn that low road. The search goes in a new direction when his younger brother who he is always bailing out of trouble, vanishes. Then it's learned he has made 2 million dollers in the past five years,but he only has $6000 in his bank account.

When the team tries to plot a strategy after they find out that Samantha has been shot and that she might be critically injured in the hostage crisis situation. Jack makes a deal with Berry so that Sam can get help and Jack goes in there and takes Sam's place.

A school bus is abducted by kidnappers who demand more and more for ransom.

When a 14-year-old violinist disappears on the night of a concert, the team follows her and her valuable violin's trail and Samantha bravely tries to recover from the gunshot wound.

When a high school sex-scandal leads to murder it is the team's job to figure out who did it and why.

When a female ex-cop-turned-bounty-hunter is shot then goes missing the team must investigatesher were about's

When a young soldier recently returned from Iraq disappears, Jack and Danny look into his disappearance only to learn that the soldier may have more secrets than they want to uncover.

The team searches for a mother and her two children, who are last seen boarding a yacht which is later found adrift in New York's Harbor with only its dead captain aboard. Meanwhile, Malone gets ready to leave the team and move with his family to Chicago.

The team searches for a recently blinded girl and her companion who disappeared during a camping trip. Vivian takes over as the supervisor, while Jack struggles to say goodbye to his family.

Lance Hamilton is a successful real estate agent in his early thirties who disappears one day after showing a house. When the team gets involved, they soon realise that Lance had more than one dealing with a local hood, Jimmy 'The Tooth' Fusco, and begin to suspect that Lance may not have been the good guy everyone thought he was. After tracking down the woman Lance had recently been spotted kissing in his office, the team needs to revise their opinion, knowing now that Lance is one of the good guys, but wondering if he's died for his beliefs.