When Sam helps Martin search for his missing and terminally-ill aunt, they discover that she's been using her nursing skills to assist other dying patients in committing suicide; his father's Alzheimer's diagnosis prompts Jack to attempt a reconciliation.

Things with Jack and Maria's divorce are getting nastier as Maria's attorney forces Jack to relive not only his childhood traumas, but also throw his affair with Sam in his face and attack his dedication to his job.

John Michaels is a 71-year-old insurance investigator who went missing after last being seen getting into a car with two strange men. While investigating his disappearance, the team finds that he had recently tried to make amends with his ex-wife and has been trying desperately to get his older daughter on the straight and narrow. Things get strange in the case though, and all is not as it seems.

Sam agrees to do a favor for a friend by looking into the identity of a young amnesiac who was found wearing expensive clothes by two police officers. The investigation leads them to a play the woman was involved in and a mugging gone wrong, then they follow the trail to the woman's past, which seems to have been the trigger for her amnesia. Jack takes some time off work to deal with his father, who is getting worse as his Alzheimers begins to take over and his kidneys fail. Jack finally convinces Frank to seek help, but it's too late, and Jack has to say goodbye to his father.

The team searches for a man who goes missing after a late night dive and try to zero in on who could be responsible for his disappearance. Meanwhile, Danny and Elena take their relationship to another level.