Following the success of part 1, "Sinister Beings 2" returns with a familiar cast.

Two senior detectives Hua Tuan Sam (played by Tran Trien Bang) and Tham Vi Luc (played by Huynh Tri Hien) work together for the Organized Crime Investigation Team and the OCTB or Point O (Organized Crime and Triad Bureau). With their intelligence and sharp observation ability, they solve many cases.