Michael Flaherty and his team grapple with a garbage strike and a political gaffe by the Mayor who accidentally insults gays. In addition, Ashley questions Mike's commitment to their relationship when is nervous about moving in together.

Michael and the Mayor work around the clock to negotiate an end to the garbage strike, which leaves Stuart in charge of the office, to everyone's dismay. And, though they just moved into a new apartment, life is so hectic that Ashley and Michael never get to see each other.

The office rallies to lift Mike's spirits after his break-up with Ashley, but he resists their best efforts. That is, until he decides he needs a friend and reaches out to Nikki in the middle of her date with the perfect man. And Paul sets a New Year's resolution to be less gullible.

While acting as the Mayor's divorce lawyer, Michael is attracted to his opponent, Laurie Parres. Meanwhile, the press thinks Paul has suffered a nervous breakdown, so Michael enlists a psychiatrist, Dr. Benjamin, to pronounce Paul sane. But his plans go awry when Dr. Benjamin unexpectedly commits Paul to an institution.

The usually indomitable Mike can't cope at the office because of upsetting news he's unwilling to share--his doctor suspects Mike has prostate cancer. The timing couldn't be worse, since the Mayor needs Mike to help write his newest book, so Mike brings in best-selling author Donald Trump to advise the Mayor on writing. Meanwhile, a chair-snatching bureaucrat is terrorizing the staffers.

Mike and Caitlin have sex. The staff works damage control but Mike ultimately fires himself to save everybody else. The staff says their goodbyes at the bar. Caitlin promises Mike that she's not going anywhere. Mike says goodbye to the mayor and walks out of City Hall for the last time. Six weeks later, Mike turns up as an environmental lobbyist in DC.