As the seaQuest undergoes inspection, Lieutenant Benjamin Krieg has a close encounter with an unknown life form while in a seaCrab in the Tonga Trench.

When the creature lets him go, Krieg discovers a treasure trove of mysterious glowing stones; stones that may mean big money.

However, is the bigger threat to seaQuest the greed that overtakes the crew or the unknown life form?

A virus found on board a sunken space station infects the crew.

As Bridger rushes to find the inventor of the pathogen, a warrior submarine from an opposing confederation arrives to cover up their crimes, even if it means the destruction of the seaQuest.

When the seaQuest visits the Broken Ridge mining colony, one of the colonists desperately pleads for the crew's help to escape from a dangerous situation straight out of the Old West.