In 1953, a worldwide invasion from Mars would have eliminated humanity had the extraterrestrial invaders not been vulnerable to the indigenous bacteria on the planet. Now an accident at a dumpsite revives the comatose aliens who then shortly attempt to resume the war they started 35 years ago.

35 years ago, Earth experienced a war of the worlds, humanity's savior being common diseases to which it had long since gained immunity. However, a Pandora's Box is opened when the invaders are accidently revived via radiation exposure, canceling the presence of their microscopic attackers. Their plot to reignite warfare is recognized only by Dr. Harrison Blackwood, who must convince others of the renewed global threat.

After a period without any further evidence of the aliens' existence, the powers-that-be try to shut down the Blackwood Project. Meanwhile, the aliens try desperately to find a way to combat the threat brought on by the radiation that is killing them.