Noah seems to think that Wade may not be totally straight after he accepts an invitation to hang out with Noah at a gay club. Alex learns that his boyfriend Trey has a secret sex life when he stumbles upon a gay Internet site Trey frequents. Meanwhile, Chance has second thoughts about moving in with Eddie.

Noah's status as a starving artist takes a turn for the worst when he gets way behind on his rent and has to sell his beloved classic car after refusing financial help from Wade. Continuing his evolution into the perfect boyfriend, Wade decides to throw him a surprise birthday party to cheer him up. But fate complicates matters when Noah gets his first studio writing job! Meanwhile, Chance goes to extreme measures to try and save his relationship; Alex makes a major career change; and Ricky's irresponsible behavior spirals out of control.

When Wade's career takes a downward spiral, Noah suggests they collaborate on a project, to disastrously tense results. At the same time, Alex monopolizes everyone's time helping to set up his new business, while trying to deal with his own jealousy over Trey's burgeoning friendship with a seemingly straight work colleague. Also, Chance's new relationship with the thuggish T-Money is not all it seems; and Ricky gets more than he bargained for when he takes an interest in a cute Latino doctor helping out at Alex's clinic.

Noah has been invited to join Dre and Wade for dinner, which rekindles creative sparks in Noah and Wade, while Dre's friend shows an interest in Noah. Meanwhile, Chance and Eddie host dinner for Eddie's bosses and their wives, and Chance happens upon an interesting coupling. Ricky continues to have thoughts about his new relationship with Junito. Alex's suspicions of Guy's friendship with Trey continue to grow.

Noah meets with British hip-hop star Baby Gat. Meanwhile, Ricky has a hard time trying to express his feelings to Junito. Alex tries to devise a plan to make his friends believe that Guy is up to no good. Chance has a difficult time disciplining Kenya.

10 years after the events of Jumping the Broom, this reunion episode written and directed by creator Patrik-Ian Polk, finds Noah and company in the middle of a worldwide public health crisis and global social justice movement.