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Pinky and Brain are genetically enhanced laboratory mice who reside in a cage in the Acme Labs research facility. Brain is self-centered and scheming; Pinky is good-natured but feebleminded. In each episode, Brain devises a new plan to take over the world, which ultimately ends in failure, usually due to Pinky's idiocy, the impossibility of Brain's plan, Brain's own arrogance, or just circumstances beyond their control.

  1. Steven Spielberg


  2. Tom Ruegger


Series Cast

  1. Rob Paulsen as Pinky (voice)

    Rob Paulsen

    Pinky (voice)

    95 Episodes

  2. Maurice LaMarche as The Brain (voice)

    Maurice LaMarche

    The Brain (voice)

    95 Episodes

  3. Tress MacNeille as First Lady, Japanese Girl (voice), Old Woman (voice), Passerby (voice), Madame De Jambone (voice), Wench (voice), Genevieve / Dot Warner (voice), Mrs. Applebee (voice), Rikki Lake (voice), Female Rock Star (voice), Sully (voice), Queen Roach / First Lady / Time Machine Computer (voice), Woman (voice), Janine (voice), Rue McClanahy (voice), Marna Strutt (voice), Baby Clark Kent (voice), Janet (voice), Katie Couric (voice), and Phyllis (voice)

    Tress MacNeille

    First Lady, Japanese Girl (voice), Old Woman (voice), Passerby (voice) and 16 more...

    51 Episodes

  4. Frank Welker as The President, The President (voice), Gollyzilla / Scientist #2 / Man in Street? Soldier #1 (voice), Ross Perot (voice), Board Member (voice), Odin (voice), Bartender (voice), Grandfather (voice), and Napoleon (voice)

    Frank Welker

    The President, The President (voice), Gollyzilla / Scientist #2 / Man in Street? Soldier #1 (voice), Ross Perot (voice) and 5 more...

    42 Episodes

  5. Jeff Bennett as Locke (voice), Hippie (voice), Baloney (voice), Schotzie (voice), Sampson (voice), Allan Fontain Bisque (voice), Wensleydale (voice), and Kilmer (voice)

    Jeff Bennett

    Locke (voice), Hippie (voice), Baloney (voice), Schotzie (voice) and 4 more...

    20 Episodes

  6. Roddy McDowall as Snowball (voice)

    Roddy McDowall

    Snowball (voice)

    5 Episodes

  7. Corey Burton as

    Corey Burton

    3 Episodes

  8. Laraine Newman as Secretary (voice)

    Laraine Newman

    Secretary (voice)

    3 Episodes

  9. Jess Harnell as

    Jess Harnell

    2 Episodes

  10. View More

Full Cast & Crew

Last Season

Season 4


1998 • 9 Episodes

Season 4 of Pinky and the Brain premiered on September 14, 1998.

Star Warners

(4x9, November 4, 1998) Season Finale

View All Seasons

Pinky and the Brain
Pinky and the Brain


Status Ended


  • See more TV shows from The WB...

Type Scripted

Original Language English


Content Score 


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  • Regular cast members (4 or more)

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