Lilly investigates a 1976 case involving a teenage girl who was beaten to death on a tennis court during a party at a plush estate. A maid to a wealthy family, Bonita Jakarta, claims she witnessed the murder of teenager Jill Shelby. Now dying of cancer, the maid who remained silent, wants the killer brought to justice. Rush reopens the case, in which two brothers were originally suspected but not charged due to their powerful society family.

Lilly re-investigates the case of a murdered church organist (John Walcutt), when his Alzheimer's-stricken widow (Isabella Hofmann) begins having flashbacks of the night in question. Lilly's investigation has both Mitchell's son, Ryan (Jimmi Simpson), and daughter, Tina (Daisy McCrackin), demanding Lilly close the search.

The 1958 death of an unknown 6-year-old boy found in a field inside a cardboard box is reinvestigated after a small suitcase with the child's picture and his old cowboy hat is left in front of a church. The new probe reveals that the rowdy boy lived at a Catholic-run orphanage and was adopted two days before his suspicious demise.

When DNA evidence reveals that a wrong man was convicted for killing 15-year-old Eve Kendall back in 1986, the team re-opens her case in an attempt to find the real killer.

A woman, who was romantically involved with Nick Vera in high school, claims that members of a fraternity might have been involved in her alcoholic sister's death in 1995. The victim's estranged husband and a bar owner are also viewed as potential suspects.

When a young girl is contacted by a man claiming to be her father, Det. Rush and her team reopen a 1988 case of a teenaged boy, killed on the same night the girl was born.

Four close high school friends each went their separate ways in 1980. Eight years later, in 1988, one of them was murdered. The homicide team receives a tip about the murder, prompting a re-investigation of the case and an examination of the friends' lives, hopes and dreams after high school.

Lilly and Valens travel to Nashville and Knoxville to investigate the 2000 murder of a country-music singer who was gunned down outside of a Philadelphia bar where he and his band had recently played. The unsolved case is reopened when the gun used in the homicide turns up.

Lilly and the team attend a colleague's wedding and are persuaded by Jeffries to investigate whether the bride killed her former fiancé two years earlier - just hours after he called off their nuptials.