In the pilot episode, Bonnie traded quips and tips with two authentic Italian chefs during an offbeat-cooking segment. The unscripted segments of the talk show, along with the talented cast of regulars, make for a truly unique comedy mix.

The Life with Bonnie cast includes the gifted and funny David Alan Grier as David Bellows, the producer who struggles with the daily challenge of … Bonnie. He's aided by the makeup and cue card artists, played by Holly Wortell and Chris Barnes, veterans of the famed Second City improvisational group. Anthony Russell portrays Tony Russo, Bonnie's sidekick piano player who comes straight to her show from his Vegas lounge act.

At home, Gloria (Marianne Muellerleile) is a houseguest more than a housekeeper. Bonnie's husband, Mark (Mark Derwin), is a hard-working family practice doctor who does his best to survive life with Bonnie. Together they are raising three young children, Samantha (Samantha Browne-Walters), Charlie (Charlie Stewart) and infant Conno

Mark is forced to work late when his long-term nurse retires, and Bonnie questions the age and attractiveness of her replacement. Meanwhile, on Morning Chicago, Bonnie cooks up pizzarustica and interviews an author who is ""out of this world

Bonnie accidentally gets involved in Mark's boss' marital problems when they learn she's having the famous marriage therapist, Dr. Bill, on Morning Chicago.