Matlock is hired to defend Brad Bingham, an aging football star with a reputation as a womanizer who was about to be cut from the team. Charlene is resistant to Ben's choice, as she believes everything the tabloids have to say about Brad...not only that, but years earlier, he'd had a brief relationship with her friend Ellen Hawley, who had tried to kill herself after they broke up. As the case continues, Charlene realises that not everything that's printed in the papers is true and that maybe Ellen wasn't quite honest with her, even though a call girl (Caryn Nelson) hired to make Brad look guilty almost convinces her that he is.

Sandra Townsend is senior counsel with Drexel, Harris and Townsend. But when she's off work she likes to let her hair down and go to the bars. When her lover threatens to expose her nightlife to her bosses, she murders him. Michelle takes the case when Matlock's former paperboy Jimmy Newton is arrested for murder (Matlock's off to California), but soon realises that Sandra, who is supposed to be the star witness, is really the killer. The problem is that Sandra Townsend is a former classmate and good friend, and Michelle just doesn't want to believe that she's lying.

When the local mayor is assassinated, Matlock's daughter Leanne comes to town to prove the case. The case takes a different turn when a judge is accused of murdering a local man's wife, and Ben and Leanne have to work out the problems in their relationship to clear Eller of murder.

An eccentric millionare tells Matlock that he couldn't solve the perfect murder if it were handed to him on a silver platter. To prove his point, he kills Matlock's friend, detective Bob Brooks, and successfully frames another man for the crime.

Matlock is the unlikely witness when a boat blows up killing Judge Michael Sterns. Had it not been for Ben's sea-sickness, he would have been on the boat. Convinced that someone was out to get him and not Judge Sterns, Matlock, Cliff and Jerri take a look through some of Ben's old cases to find out who did it, and Matlock takes on the case of the man accused of the crime, a former lawyer who had been disbarred for jury tampering exactly five years earlier.