"Friends, Lovers, Brothers, and Others" was the technical second but chronological third episode of South of Nowhere that aired on November 11, 2005 on the teen drama channel, The-N.

Ashley is not too impressed with Spencer's new gal pal. Meanwhile, Clay finds common ground with someone he least expected and Madison puts Glen and Aiden in a possibly dangerous situation.

Spencer wakes up with Ashley and they talk about what happened the night before. Ashley and Spencer go out to dinner with Ashley's father and afterwards find out he died, and at his wake Ashley find out she has a half-sister.

Ashley has only had Kyla as a sister for a few weeks, and she's already sick of her. Things get ugly between the two, and a VH1 special about their dad makes the situation even worse. Plus, fact that Aiden is crushing on Kyla isn't helping much either.

Spencer accepts a date with Aiden, which ends up confusing her even more. Clay faces trouble while searcing for his birth mother, while Paula and Arthur try couple's counseling as a way to deal with their issues.