Florence, Béatrice, Manue, and Julia meet for drinks as they don't have custody of their children. But the next day, Florence is depressed as she is alone in her new flat with her dog, Bernie, and unable to write her next show.

Florence tries to somehow get down to writing down her show with Pascal. She enrolls in a yoga class in order to take control of her life, but Death enters her home in the disguise of a strange man.

Florence secretly attends the dance rehearsals of her daughter, Toni, and there she meets Valentin. She asks for antidepressants from her doctor to fight against her panic attacks. Pregnant Béatrice informs Florence that she wants an abortion.

The retouched photograph that Florence chose for her show's poster does not receive approval from all her friends. Florence prepares for her dinner with Valentin but has to face Death, who often turns up at her home.

When Florence is ready to receive a lifetime achievement award, she gets burdened with a paranoid bodyguard as she attends the ceremony with her girlfriends. Upon her arrival, Florence finds that her outfit matches another VIP's dress.

In the midst of depression, Florence spends her days bedridden. Pascal tries to amuse her and make her smile again, while Death keeps her company. When Florence discovers Bernie is at the vet, she is determined to bring him back at any cost.

The imminence of her next show restores Florence's joy of living. As she prepares to regain custody of her daughter, she is invited to the grand opening of celebrity chef Joshua Lebon's new restaurant, where she goes with her girlfriends.