Mourning the death of Prue, Piper and Phoebe must now come to grips with the loss of their oldest sister, and the loss of the Power of Three. However, The Source discovers an unknown sister - the daughter of Patty and her whitelighter Sam, who had been kept hidden, Paige, the now-youngest Halliwell can restore the Power of Three and reunite the sisters' strength as witches.

A vampire queen tries to dethrone Cole as ruler of the Underworld and attempts to turn Paige against her sisters. Meanwhile, Phoebe begins to feel under the weather.