The Meaning of Life is an Irish television programme, the first series of which was broadcast on RTÉ One in 2009. It is presented by the veteran broadcaster Gay Byrne. Each episode involves Byrne interviewing a well-known public figure. The series is broadcast each Sunday night at 22:20.

In 2010 The Meaning of Life returned for both a second and, later, a third series. Interviews with former Taoiseach Bertie Ahern and actors Gabriel Byrne and Brenda Fricker during the second series attracted media attention when they spoke of their religious habits and child sexual abuse respectively.

Gay Byrne appeared on The Late Late Show on 18 December 2009 to discuss the programme.

A fourth series soon followed. Then a fifth series from January 2012. And a sixth in October 2012. And a seventh in January 2013.