The NCIS team hunts for a heist crew that robs a Los Angeles casino with military-grade power. Also, Kensi and Deeks hear exciting news regarding the adoption and Callen takes a big step in his relationship with Anna.

While Agent Rountree and Fatima are searching for Kilbride, who has been MIA, they are ambushed and learn that every member of the team has a $200,000 bounty on their head via the dark web. The NCIS team must save Agent Rountree and find Kilbride while every cartel, hit man, gang and psychopath hunts them down.

The crossover starts on NCIS S20E10 Too Many Cooks (I) and NCIS: Hawai'i S02E10 Deep Fake (II).

When Sam's friend Tom Olsen finds himself being hunted down by enemies from his past, the NCIS team must find out who is after him.

When a mystery woman attacks the founder of an AI company, the NCIS team must identify the woman before the next major global conflict ensues. Also, Kilbride's ex-wife, Elizabeth, comes to visit and asks him to think about reconnecting with their son.

When an ATF agent goes missing, the agency seeks help from the NCIS team to investigate stolen military-grade weapons and locate the agent. Also, Callen and Anna continue to plan their wedding, Rountree’s sister interviews for medical school, and Sam encourages his father to take part in the drug trial.

The NCIS team continues the case with ATF and the stolen weapons. Also, Callen and Anna decide on an impromptu wedding.