The NCIS team searches for a stolen painting valued at $40 million after online chatter indicates the artwork is being sold on the black market to fund terrorist activity.

The NCIS team links the theft of an undersea drone prototype to a video game streamer’s elaborate party. Also, Callen and Sam cross paths again with insurance broker Katherine Casillas, who insures the gamer’s property and processions.

After a rise in deaths caused by black market opioid use, the NCIS team links the street drug to funding for terrorist activities

The NCIS team investigates the murder of a Naval warfare engineer at a spoken poetry event. Also, Callen asks Nell to assist him in a worldwide search for Anna's whereabouts.

The team assists the DOJ in the investigation of an arsonist who targets an FBI safe house that's protecting a political activist seeking asylum; Eric deals with the aftermath of Nell leaving the team.

Before Christmas, Hetty assigns Callen the case of his former foster brother and his wife who, upon reentry into the U.S., are framed for smuggling drugs across the border in her oxygen tanks. Also, Deeks is struggling with losing his job at NCIS.