Rachel's pediatrician drops her as a client because she calls him incessantly to ask about any insignificant issue concerning Emma, so now she must find a new one, which puts Ross in an awkward situation. Meanwhile, Joey arranges a blind date for Phoebe. Also, as Chandler and Monica are preparing to leave for Tulsa, Monica receives a job offer from a prestige restaurant in Manhattan.

After Phoebe has a talk with Ross, it prompts her to realize that she's never had a long term relationship. Monica makes a startling discovery while visiting Chandler in Tulsa. Also, Joey goes on a date with an attractive woman and discovers that her apartment seems really familiar, although he doesn't remember sleeping with her before.

Ross and Rachel hire a nanny for Emma named Sandy and things seem to be going great. However, Ross is uncomfortable having a male nanny. Meanwhile, Chandler becomes upset when Monica says that somebody from her new job is the funniest guy she's ever met. Also, after Phoebe and Mike decide to take their relationship to a new level and exchange apartment keys, Phoebe gets a surprise visit from her ex-boyfriend David.

Ross finds a way to make Emma laugh - singing Sir Mix-A-Lot's "Baby Got Back." Needless to say, Rachel isn't as amused, once she finds out. Meanwhile, Phoebe meets Mike's parents and tries her best to leave a good impression. Also, while viewing Richard's old apartment, Joey and Chandler discover a video tape with Monica's name on it, which causes Chandler to freak out, since he thinks it's a sex tape.

Joey becomes convinced that Monica is having an affair, after Chandler sneaks back into town without him knowing, in order to have some alone time with his wife. Meanwhile, Rachel and Phoebe have a girls night out, and Rachel gives her phone number to a guy they meet at a bar. Also, Ross and Mike try to hang out together but it doesn't go very well, since they can't find a common interest to talk about.

Gavin gives Rachel a very interesting birthday gift while Ross begs Joey to stay away from Emma's hot new nanny. Meanwhile, Mike meets and then accidentally murders Phoebe's unusual pet.

A night at Mike's piano bar gives Monica a very showy moment in the spotlight. Ross struggles to move on after witnessing Gavin and Rachel kiss. Meanwhile, Chandler employs his secret skill to repair Joey's botched eyebrow-waxing job.

While reviewing their monthly expenses, Monica and Chandler discover that their situation is less than stellar. This results in Monica asking Joey to lend her some money without telling Chandler. When Chandler eventually finds out, Joey comes up with a lie that Monica needs the money for breast enhancement procedure. Meanwhile, Phoebe gets really excited as she and Mike decide to move in together, but her excitement quickly dissipates once she discovers that Mike doesn't see himself getting married ever again. Also, Rachel's attempt to baby-proof the apartment tampers with a frustrated Joey's sanity.

Chandler's jokey entry on his and Ross's college website leads to a faux burial service for the allegedly dead and obviously unpopular Gellar. Joey refuses to give Emma his favorite stuffed animal. Phoebe begs Monica to help her avoid a post-breakup tryst with Mike.

Chandler gives David advice that culminates in David deciding to propose to Phoebe. However, Phoebe is still in love with Mike. Monica meddles and calls Mike, who shows up in Barbados and interrupts David's marriage proposal with one of his own. Phoebe chooses Mike, although she doesn't accept his proposal. Meanwhile, sparks fly between Ross and Charlie when they spend some time together rewriting his speech.

Charlie and Joey break up, and Rachel finally tells Joey about her crush on him. He decides nothing can happen because Ross is a good friend, but after he sees Ross and Charlie kissing, he heads back up to Rachel's room where the two kiss and shut the door. Meanwhile, Monica and Mike compete at a game of ping pong.

Still in Barbados after Ross' keynote address, the friends cope with a variety of dilemmas. Ross has kissed Charlie, although she is still officially dating Joey. Joey and Rachel have kissed as well, but they agonize over how to tell Ross. Mike followed Phoebe to the island and proposed, despite his being in a relationship with someone else. And Monica has developed big hair, due to the humidity.

To help her younger sister, Amy, become a more responsible person, Rachel overrides Ross' strong protests and allows Amy to baby-sit Emma but soon regrets that decision. Phoebe unknowingly thwarts Mike's "anniversary" surprise for her. Monica and Chandler become concerned when Joey tries to use big words in a recommendation letter on their behalf to a child adoption agency.

Monica and Chandler nervously prepare for a visit from an adoption worker who will decide if they would be suitable parents. Phoebe and Mike opt to have a small wedding and donate the extra money to a children's charity--only to demand it all back later. And Ross tries to help Rachel overcome her fear of swing sets so baby Emma can enjoy the playground.

Phoebe's wedding planner, Monica, makes everyone around her crazy--until Phoebe fires her. Phoebe's big day becomes disastrous as deliveries go awry and New York is hit with the worst snowstorm its seen in 20 years, forcing plans to change. As a substitute for Phoebe's incarcerated father, Joey takes his role much too seriously. Chandler and Ross discover at the rehearsal dinner that neither of them has a part in the wedding; however, Mike needs to replace a groomsman — he lets Phoebe choose one of them, but she gives the job to Rachel.

Monica and Chandler visit their house, which is in escrow, where Joey is comforted about losing his friends by the 8-year-old girl who presently lives there. Phoebe learns she can legally change her name to whatever she wants, so she considers something more exotic. Ross gets tenure at his job. Rachel's boss is sitting next to her in a restaurant while she's interviewing for another job.

Ross and Phoebe chase Rachel to the airport, but end up at the wrong one. Chandler and Monica finish packing for their move to the suburbs, and Joey loses Chick Jr. and Duck Jr. in the foosball table.

The series finale finds Rachel, Monica, Phoebe, Joey, Chandler and Ross embarking on the next chapters in their lives. The six of them have been there for one another through all the ups and downs of becoming adults. Now it's their last day together, and it's one of momentous events and last-minute surprises. Even as the friends make major decisions, they share a bond that will last forever.