As a total eclipse casts its shadow across the globe, a genetics professor in India is led by his father's disappearance to uncover a secret theory -- there are people with super powers living among us. A young dreamer tries to convince his politician brother that he can fly. A high school cheerleader learns that she is totally indestructible. A single mother struggles to make ends meet to support her young son and discovers that her mirror image has a secret. A gifted artist, whose drug addiction is destroying his life and relationship with his girlfriend, can paint the future. And in Japan, a young man develops a way to stop time through sheer will power. Yet, unbeknownst to them all, their ultimate destiny is nothing less than saving the world...

Outside a bizarre, gruesome crime scene, Los Angeles beat cop Matt Parkman is the only one who can hear the cries of a missing little girl. Claire almost reveals her secret ability to the entire school after learning that her injury attempt tape has disappeared. Thinking she's going crazy, Niki loses another block of time after waking to find some brutally murdered thugs in her garage, only to be confronted by Social Services about son Micah. While office drone Hiro investigates New York, Nathan confronts Peter following his plunge off a building.

Suresh finally tracks down one of his father's fabled genetically advanced "supermen." In Las Vegas, Hiro's plan backfires when he cautiously turns time to his advantage at the gambling tables. Niki's mafia debtors use their leverage to their benefit in a more elaborate scheme, while Nathan pays a personal visit to a wealthy Vegas contributor to raise additional campaign funds. Following a tragic turn at a bonfire, Claire's uncanny healing abilities are put to the ultimate test, but according to Issac's paintings, her future could be fraught with even more peril

Meanwhile, Matt's abilities are gauged by a pair of men who seem to know a great deal about people with special gifts.

Confused after losing track of another block of time, Niki finds the police on her doorstep, searching for her fugitive husband D.L. Hawkins. Claire confesses to her father. Hiro and his friend get jumped by some Vegas high-rollers. Peter receives a life-changing message from an unlikely source.

Meanwhile, Matt secretly uses his mind-reading ability to anticipate his wife's needs. Dismayed by recent events, Suresh makes plans to return to India to lay both his father's remains and his research to rest.

Facing a crisis involving her son Micah, a distraught Niki reveals her recent personal struggles to a friend. Pushing aside his own issues at home, Matt assists Audrey's investigation into another bizarre murder, but their pursuit of mysterious serial killer Sylar takes an unexpected turn. After failing to act like a "superhero" when faced with danger, Hiro questions his heroism. Nathan and his wife Heidi strategize how to win the congressional election. Claire is shocked to learn where her missing tape wound up.

Meanwhile, her father is disturbed by news from one of his associates.

As the clock turns back six months for all of the "Heroes," Mohinder's father Chandra Suresh arrives in New York to begin his quest to find individuals with extraordinary abilities, and meets someone all to eager to be special. Peter celebrates his graduation from nursing school, and learns that Nathan plans to prosecute a case that could mean trouble for the entire Petrelli family. A surprise visit from her father brings out the worst in Niki. Hiro attempts to be a hero and change the future for someone important. Claire joins the cheerleading squad and makes a curious discovery. Mr. Bennet and the Haitian meet someone special.