An arm in a shark's gullet and a girl who was shot at sea lead the team to a smuggler who was running Cuban refugees and cocaine in a foundering ship.

When a priest is found dead in his rectory after being brutally shot, Megan, Calleigh and Speedle must untangle a messy web of familial issues that lead to his death. Elsewhere, Horatio and Eric attempt to solve the emotional case of an exploded vehicle, which was home to a mother with child.

Horatio, Calleigh and Speedle investigate the death of an exotic male dancer found dead after a sexual party, and must dig through the evidence to discover a motive. Meanwhile, Eric and Megan investigate the death of a man involved in diving that mysteriously died after climbing onto a random boat.

Horatio and his team must uncover the evidence in the brutal murder of an entire family in their own home. The only survivors are a blood-soaked toddler, and the father who's in surgery. The immediate assumption is that the mother is responsible – post-partum depression – but the evidence discloses a different outcome.

During a typical morning rush hour in downtown Miami, an unseen sniper chooses three victims at random and opens fire, killing each with a single shot to the head. Horatio and his crew rush to the scene, which is quickly mobbed by TV news reporters eager to spin the murders into a national story. The initial investigation doesn't reveal much, as there were no witnesses and little evidence remains. But the case heats up when the sniper strikes again, killing two more innocent people.

Horatio, Speedle and Calleigh root through the evidence in the homocide of a strange, and unorthodox college professor when they find him tied to a tree. Elsewhere, Delko and Megan investigate a car found in the water with a dead body in the trunk, and immediately suspect an insurance scam.

The team investigates the death of a young model, whose body was found near a juvenile detention camp for girls. Across town, Delko and Speedle probe the bizarre death of a man who was apparently burned from the inside.

Horatio and Speedle investigate the slaying of a hooker who is found dead under a bed in a plush beachside cottage, her naked body having been stabbed 23 times. But the crime scene yields few traces of blood because the killer bathed the victim in the cottage's tub with cardamom soap. Across town at an urban gas station, Calleigh and Delko attempt to uncover why a German tourist was gunned down in an apparent carjacking. They learn that a masked assailant approached a vacationing couple's rental car, shot and killed the husband, but left the wife unharmed and then fled the scene.

Horatio investigates the death of a man who accidentally inhaled a lethal combination of chemicals in a neighboring house after he went inside to retrieve his cat. Elsewhere, a resident of a retirement community is found dead in a pool of blood, an apparent victim of a vicious attack.

Shortly before Horatio is set to testify at a high-profile murder case in which the defendant is the husband of a city councilwoman, he's given new facts that could prove the man is innocent. The information revolves around the discovery of a second victim who matches the profile of the first one and was killed in a similar manner. If the man on trial isn't guilty, then Horatio fears that a serial killer may be on the loose.