Campbell ends up having to take care of Nick after he's let out of rehab. Nick suggests that Campbell should sell his kidney in order to keep funding the failing video company. Leonard rejects Ben's sexier and hipper new company catalogue. Nell discovers that a former childhood bully has become an actress on a popular daytime soap opera. Henry recieves news that his father has passed away.

The story about three Los Angeles friends begins; Campbell, the manager of a band whose career ends when the bandmembers end up in either prison or rehab. Nell, an ad exec who doesn't want to commit to her job. And Henry, a writer who can't seem to further himself past a job at an adult internet site.

The story begins with Campbell finding it difficult to take part as best man at his brother Ben's wedding since he may have feelings for bride-to-be Jane, who Campbell dated at one point in the past. Nell asks Henry to move in with her, a rash decision she may soon regret. Henry finds himself attracted to his attractive-but-married boss Charlotte.