While helping to track down a runaway, Jill, who is involved with drugs, Johnny is exposed to a drug that causes him to start getting weird (weirder than usual) visions. He insists on trying to find Jill, despite the concerns of Bruce and Sarah. Confusing matters further is that Jill's boyfriend is in trouble with his supplier. The boyfriend gets killed and Jill and Johnny go on the run. In the final showdown, Johnny manages to fight past his hallucinations and knock the drug dealer off a high ledge, while Jill is reunited with her mother.

Isolating himself from a demanding public, Johnny gets visions of himself disappearing after making contact with something belonging to a shut-in, Jeffrey Grissom, brought in by his delivery man. Johnny briefly visits him and Grissom talks about wondering where his old home was, then Johnny returns the next day with information to find out Grissom and any trace of him have completely disappeared. Johnny is determined to follow up when he gets a vision of people removing Grissom and the new family moving in. Johnny gets visions of people going through his own home as well and gets close enough to the people following him to get a vision of Grissom in a new home and visits him there. Grissom reveals he is a retired spy kept buried by the U.S. government due to valuable knowledge in his head.

A wild old high school friend, Jason, comes to see Johnny seeking a vision of the future as he will be dying of a heart condition. Johnny sees him receiving a successful heart transplant and gives him the good news, but later gets a vision of Jason's sister Kate being killed in a driving accident and becoming the donor. Johnny later gets a vision of the other driver's license plate while Jason takes a turn for the worse, then sees a vision of him and Kate arguing which leads to her going out and getting in the accident. Johnny soon realizes even if he saves Kate and gets Jason a heart through Purdy's connections, someone else who would have received the heart will die. Johnny tracks down the drunk driver, Patrick Hanchin, and confronts him, but sees that even if Johnny stops him from killing Kate, he'll hit a school bus.