Bounty hunter Brisco is hired by the West's most powerful robber barons to bring down the John Bly gang.

Brisco and Socrates head south of the border when the Westerfield Club orders them to recover some stolen guns.

Socrates sends out an S.O.S. to Brisco when he loses Westerfield Club money to Brett Bones, a member of John Bly's gang, in a poker game. Brisco, Bowler, Socrates and Wylie set up a scam to get the money back and put Bones in prison.

Brisco and Dixie find romance while on the run from an assassin in pursuit of Dixie, who has incriminating evidence against a politico.

Brisco pursues Dixie's ex-husband, who proposes that he and Dixie steal away after he heists a supercannon.

Brisco helps Dixie and her sister Dolly battle a mob seeking control of Reno gambling.

A band of warriors are after the infant heir to the Chinese throne.