The Mutant X team learns about Lexa's estranged twin brother when he becomes the main target of an underground operation harvesting mutant organs.

Discovering that their teammate Lexa is the subject of a covert experiment that is controlling her, the Mutant X team hunts for the doctor responsible.

Brennan battles with a Guardian of the Prophecy to stop the late mutant Ashlocke's plan from beyond the grave of world domination.