Meg becomes an intern for Mayor West. Brian, who is sure that the mayor is corrupt, tries to out him. Brian and Stewie, while undercover, discover that Meg is more than just an intern. Meanwhile, Peter and Lois go back to their folk singing days at a local talent show. When they begin using drugs, Chris stages an intervention.

Peter's mom gets a divorce. Peter feels abandoned until he sees a father figure in his mom's new boyfriend, Tom Tucker. Meanwhile, Brian gets his own NPR style show on the radio.

Peter convinces Brian to move in with his girlfriend Jillian and Stewie tags along to help pay the rent but he tries to interfere with their relationship. Meanwhile Meg and Chris get jobs at the convenience store where Chris befriends the manager Carl who leaves Meg to do all the work. Carl soon fires her and promotes Chris to the co-boss.

Peter gets a lasting supply of gasoline for the year, so the family decides to use it to take a road trip to the Grand Canyon. They pack up and hit the road, but it takes them a while to realize that they had forgotten to bring Stewie with them; when they do, they must make their way home posthaste.

In this murder mystery special, The Griffins as well as all the other major characters become trapped in a mansion while they are killed off one by one.

Stewie’s favorite thing after his teddy bear, Rupert, is Christmas. So when he hears that Santa is making an appearance at the mall, he begs Brian to take him so that he can tell Santa in person what he wants for Christmas. Brian begrudgingly takes Stewie to the mall, only to get the brush-off from Santa. As a result, Stewie and Brian travel to the North Pole to find Santa and teach him a lesson in holiday cheer.

Brian and Peter are required to attend a 12-step program to deal with their drinking problems; Death gives Peter a glimpse of what life would be like without alcohol.

Peter and Chris go to fat camp where they cross paths with a serial killer who targets overweight kids; an album cover frightens Stewie.

Chris leaves home to move in with Herbert while Stewie and Brian become obsessed with singer Anne Murray.

When Mayor West is put on trial for murder, Brian is the lone holdout voting "not guilty," and he tries to persuade his fellow jurors that there's a reasonable doubt of the Mayor's guilt.

On the night before Thanksgiving, Brian and Peter drunkenly devour the holiday bird, and then must go out to find a replacement. In Peter absence, Chris attempts to step up and become the man of the house.

Peter's friends roast him. With his feelings hurt, he seeks refuge by befriending a group of gossipy women.

Stewie doesn’t like Brian’s stand-up comedy jokes, so the two of them fight. To get back at Brian and make him jealous, Stewie builds a robot friend. But when the robot outsmarts Stewie and dumps him, Brian and Stewie reunite. Meanwhile, Lois forces Peter to get a new mattress.

Quagmire discovers the “dating” app Tinder, forcing Peter, Joe and Cleveland to intervene and save him from his soul-sucking hedonism. Meanwhile, Stewie finds out that he has scoliosis and learns the perks of his latest diagnosis

In an attempt to avoid eating the healthy food that Lois forces him to eat, Peter opens up his own food truck with fattening foods. Meanwhile, Meg joins a roller derby team, despite Chris thinking it’s too dangerous

After Brian sustains an injury, Lois gets hooked on his painkillers. Meanwhile, Cleveland refurbishes Peter's ping pong table, which becomes the hot spot in the neighborhood.