Stan goes to great lengths to compete against his rival, Chuck White, and become the new deacon of their church. Meanwhile, Roger's "temporary problem," which Stan tries to use to his advantage, causes all sorts of problems for Steve, Betsy, the rest of the family, and eventually, Stan.

Stan has to throw a party for his boss and assumes his wife Francine will do all the work, but she refuses. With Stan as party planner, the event turns into a disaster. As a result, Stan's boss relocates Stan and his family to Saudi Arabia, where they quickly get a taste of life on foreign ground. As American and Arabian social norms clash, gender wars heat up.

Stan wants Steve to be popular and goes to desperate measures giving him steroids to make him bigger, better, and part of the in-crowd at school. But when the steroids have an unexpected side effect, Steve gets a lot more attention than anyone expected. Meanwhile, after Hayley makes a movie about Francine's life as a housewife, Francine is determined to start a new career as a doctor.

Stan has his heart set on speaking at the Republican National Convention on behalf of the Langley chapter, but when they pass him up for another candidate, he accepts the only endorsement he gets from the local chapter of Gay Republicans. While the people around him disapprove of his new lifestyle choice, Stan decides to follow his heart to speak on their behalf.

When Stan feels like he's not climbing the ladder fast enough at work, he turns to his lifelong ambition of making festive teddy bears. However, when he realizes that making a quick profit takes a lot of work, he resorts to using illegal aliens as cheap labor. Meanwhile, Hayley sees her father's new business model as an atrocity and takes matters into her own hands by calling Uncle Sam.

When Stan's mom gets dumped by yet another boyfriend, she comes running to Stan for support, which he willingly provides (yet again). Francine, feeling threatened, seeks to loosen this umbilical cord, with Roger's help. Meanwhile, Klaus inadvertently gives Steve a fish disease called "ick."

Francine is out of town, giving Roger an opportunity to host spring break at the Smith house for visiting college students, one of whom becomes the straying Stan's "spring-break buddy." Meanwhile, cable music-channel host Carmen Selectra decides she wants to make Steve her sexual conquest.

Hayley goes on a rampage after her boyfriend breaks up with her, but she calms down when she begins dating Stan's CIA body double, Bill. Meanwhile, Steve and Roger get jobs separating male and female chicks at a Chinatown hatchery.

Steve connects with his ne'er-do-well paternal grandfather, whom Stan despises for many reasons, not the least of which is that he never taught him to ride a bike. Meanwhile, Hayley must find an internship quickly, so Roger hires her to tend his bar.

Steve and Stan, who don't have much in common, try to bond on a road trip to Albuquerque in search of a pair of the distinctive DeLorean doors to complete a car that Stan has been building. Meanwhile, Roger, Hayley and Francine decide to have an adventure of their own, but they can't decide what to do.

Francine and Stan swap spouses with their gay neighbours Terry and Greg when Terry's dad, a former football player who doesn't know that his son is gay, arrives for a visit. Meanwhile, Steve goes on a drunken bender.

When Stan admits that his heroes include the 1980 U.S. Olympic hockey team, Roger confesses that he played on the team; Reginald tries to win over Hayley by taking her to a concert.

When Stan realizes that he might never fulfill his dream of becoming a Best Man, he convinces his last single friend, Principal Lewis to marry the school’s Superintendent and to choose him as his Best Man. Stan invites Lewis’ old friend from prison to the wedding, only to discover a secret that could prevent the wedding from happening at all. Meanwhile, Roger finds the perfect pair of shorts, and an encounter with Ricky Martin makes him question his self-confidence.