During Vegas's latest Heat wave of triple digit temperatures, Gil and Catherine investigate a baby locked in a car. Warrick investigates a man dead of an apparent heat stroke in his house. Nick and Sarah investigate a woman's body found floating in the lake with a blow to the head.

When a student is arrested and tried for the murder of a popular high-school girl, the suspect's 12-year-old sister confesses to the crime. This results in the judge giving the prosecution 72 hours to re-examine the evidence before the jury delivers its verdict.

Coming straight from the perspectives of five people: Donna, Rebecca, Jack, Lou and Ray. All with one thing in common. They’re all dead. Brass and Catherine get to handle the case of Donna, who’s a cop from San Francisco, moonlighting as a bodyguard. Warrick and Greg work the case of Rebecca, who’s a former supermodel who died while hiking with her new husband Gavin. Nick and Sofia handle the case of Jack, a returning veteran from Iraq, who was killed in front of his wife and baby daughter who he just met for the first time. Grissom and Sara take the case of Lou and Ray whose bodies were found in Lou’s garage.

Three tourists are beat up, badly. One is dead, Alfonzo. Jessica is badly beaten but is still alive. Stanley, the last tourist is saved by Greg who ends up severely hurt in turn and ends up hospitalized after having to make a life altering decision.

Grissom and Sara may be secret lovers, but they still find ways to surprise each other like when their religious beliefs surface when two nuns find a body of a woman crucified on a makeshift cross. The woman was found in a church where the priest may be a man of sin instead of a man of God.

While investigating an elderly woman's murder, Grissom receives a miniature crime scene replica; Greg attends a hearing to ascertain his culpability in a teenager's accidental death.

Grissom investigates when a worker at a poultry processing plant is found dead in a stun bath used to electrocute chickens before they are slaughtered. Nearby, a miniature replica of the crime scene is discovered. It's eerily similar to two other replicas left at scenes of homicides. Also, a man and a dead woman are found stuck in cement at a construction site; and an elderly Russian woman is discovered dead in her apartment with her head in a gas stove, but Warrick thinks she was murdered.

Catherine testifies in a murder trial in which a man is accused of murdering his own mother three years ago, but the suspect is found not guilty. Catherine, however, believes he did commit the crime and that he may also have killed two other people, so she sets out to find the other victims. Grissom prepares to leave on a four-week sabbatical.

After a man is killed in his limousine, Greg finds that the murder victim has ties to the man he had to kill in self-defense. The team finds that the brother is involved in this investigation and has to deal with him and his hostile mother.

The CSI labrats take center stage to discuss the case of the Miniature Killer.

With time, the weather, and the desert against them, the CSI team must work together to find Sara before she dies from the miniature killer's attack.

When a band member of Rascal Flatts is electrocuted by his own guitar during a concert, the CSI team investigates if it was a case of foul play.

When a young boy is found murdered, the CSI team uncovers evidence that may link his death to an old case that recently resurfaced.

Catherine and Detective Vartann are thrown together in a hotel room for 24 hours as they stake out a duo making drugs in the room next door. Meanwhile, Nick and Langston work a case that involves a fetish which has become big business in Vegas.

Following his escape, Nate Haskell, the notorious "Dick & Jane" killer, resurfaces when he e-mails a disturbing video to the father of one of his brides, threatening to take her life.

D.B. Russell leads the CSI team on a hunt to find Morgan and Ellie Brass following their kidnapping by a ritualistic killer.

The CSI team reopens a 10-year-old murder/suicide case when the sole survivor claims her accused father was innocent.

The CSI team investigates a death involving a vintage Rolls Royce and a chrome-covered victim.

The CSI team investigates a murder with ties to two teenaged kidnapped girls.