Grissom is called to a murder of a 17-year-old in a casino penthouse. Sophia Curtis (Louise Lombard) joins him in his research, she normally works in the day-shift. The entire team gets involved when its discovered that a kiddnapping took place along with the murder.

The swing shift has a busy time. Warrick looks into the murder of man by someone who apparently needs a wheelchair. Nick looks into the murder of woman in the subculture of the narcocorrido, songs about drug murders. The night shift is slow and lends help to Catherine's team.

An up-and-coming movie star is found dead in his hotel room after a night of partying with his groupies.

Catherine and Brass investigate the case in which a man is found dead in a dumpster. It soon turns out the man had a serious food problem. The trail of his death soon leads to a hotdog-eating contest.Meanwhile, Nick and Sara investigate a not-so-amicable divorce with a bizarre twist. So bizarre it eventually lead to murder when both are found dead and it looks like the dog killed one of them.

The CSIs must investigate when a party girl is injured and killed in a traffic accident.

The CSI team is lead into the rap music world as they investigate the murders of three rival teen rappers.

Three tourists are beat up, badly. One is dead, Alfonzo. Jessica is badly beaten but is still alive. Stanley, the last tourist is saved by Greg who ends up severely hurt in turn and ends up hospitalized after having to make a life altering decision.

Nick and Keppler investigate the bizarre world of the black market sales of body parts after they find a body that has been burned and the organs removed. The rest of the CSI team investigates the death of rich woman who was killed in her own home.

After a man is killed in his limousine, Greg finds that the murder victim has ties to the man he had to kill in self-defense. The team finds that the brother is involved in this investigation and has to deal with him and his hostile mother.

The team investigates an underground mob. Warrick ends up becoming the prime suspect in a murder that's related to the mob, and his addiction to pills starts to have a significant impact on his job as a CSI.

Brass, Catherine, Grissom and Nick work the case of a female victim found in an apartment building with a gun shot wound. Drops becomes a person of interest during the investigation, even though he is still in jail.

Catherine comforts Warrick when he is accused of murdering a famous Vegas gangster and even he is uncertain of his guilt or innocence.

The team has a hard time investigating a shooting in Koreatown when none of the witnesses will talk about the crime.

The detectives search for the murderer of FBI agent Billy Ray Jackson, only Billy Ray isn't really an FBI agent, and neither are his impressively capable partners, Miles Baker and Emma Solomon.

Langston is shocked when his former student is found murdered and becomes the focus of a CSI investigation into the world of Mexican wrestling.

The son of a notorious killer is arrested on suspicion of murder, and the CSI team must overcome their natural prejudices against the boy's antecedents in order to track the true culprit.

A bowling tournament is disrupted when an important piece of evidence is uncovered, leading the CSIs to investigate a murder at the same bowling alley.

A legendary comic from the good old days of Las Vegas is set to reunite with his partner on stage for one night only, until one half of the famous duo is found dead.

The team investigates when a woman is attacked by a shark in the pool at a Las Vegas casino.

The Crime Scene crew investigates the gruesome murder of a high-powered, widowed lawyer, while Ray faces that it is time to move on from his old life.

The investigators attend the gala grand opening of a mob museum, only to witness an attempted hit on mob lawyer and former mayor Oscar Goodman.