Grissom and his team investigate the death of a first class passenger on a flight to Las Vegas. The investigators are forced not only to examine the physical evidence, but also to interview all of the first class passengers to get their personal accounts of the incident.

Grissom is called to a murder of a 17-year-old in a casino penthouse. Sophia Curtis (Louise Lombard) joins him in his research, she normally works in the day-shift. The entire team gets involved when its discovered that a kiddnapping took place along with the murder.