Grissom and Catherine investigate when a leg is found severed from a body in a lake. They suspect the husband and boyfriend. Meanwhile Sara and Nick investigate a fraternity pledging gone terribly wrong.

Catherine violates department protocol when she takes the case of a rape accusation against her ex-husband. Warrick and Sara search for the missing bullet that will either exonerate or indict a cop for murder. Grissom and Nick investigate when a female skeleton is found under a house buried in cement.

Grissom and Sara investigate a bug riddled body found in the desert. Warrick and Catherine look in to the theft of some valuable art. Nick gets to find out why a missing woman's car is found at the bus station. Warrick is suspected of having gambled on duty.

A bomb goes off in an office building killing one and injuring many more. The chief suspect is a security guard who left minutes before the explosion and has knowledge in bomb making. Nick helps his prostitute friend again. After giving in to his passion, she is found dead the next morning. Naturally, Nick is a suspect and to make it worse, Ecklie has the case.

A body is found in a pottery store in what's apparently a robbery that was interrupted. Fingerprints at the scene seem to match a twenty year old kidnapping case. Sara and Warrick look into a case where a woman burned to death in her home. The woman was burned to an ash but only the chair she was in was burned, the rest of the house is fine. Sara believes they have a case of spontaneous combustion.

Two women run over a deaf man but they didn't kill him- he was already dead. Grissom has to find out who did it and he's not getting help from the deaf man's school. Catherine and Nick investigate an apparent mob hit that leaves five dead in a coffee shop.

Grissom investigates a possible suicide at a high-profile construction site. Catherine takes on a case with a teenage boy who dies while in session with his female psychologist,

Grissom and Sara investigate when a man's body, which has been doused with lye, is found buried in a park; Nick tries to determine how a hiker apparently drowned in a desert.

Distracted by an attractive passenger, an Indian taxi driver feels his cab strike something at a suburban intersection. When he gets out to check, he finds a teenage boy pinned beneath the left rear tire, apparently killed on impact. The cabbie jumps back into the taxi to call for help, but a mob of angry onlookers - all of them white - drags him out and beats him for the crime. When Grissom arrives on the scene, he discovers that the teen has been eviscerated and has stab wounds, but shows no signs of having been struck by the cab.

Grissom investigates the murder of two men that leads him to a new encounter with Lady Heather. Catherine is desperate to find out what lead to the near death of her daughter and why her ex, Eddie, disappeared.

An elderly woman crashes her car into a crowded restaurant. One of the patrons is Sara's paramedic boyfriend. Grissom and Nick investigate the possible carbon monoxide murder of a woman in her home.

Warrick's appearance at the preliminary hearing on a rape and murder case goes terribly wrong when the only piece of evidence is thrown out on a technicality. Grissom and the team have 24 hours to make the case with new evidence or the killer will go free.

The lone holdout on a jury is found dead in the jury room. The eleven jurors who were voting guilty and who hated the dead juror are the natural suspects. Nick reopens a four year old case when the sister of the victim comes forward with new evidence.

Three little CSIs (Grissom, Sara, and Nick)respond to an electrocution at a casino. The casino is hosting Japanese antiquities. The electroctution is just a ruse to steal the central piece of the exhibit. Catherine and Warrick deal with a vampire murder.

A woman is found dead in a hotel suite with symptoms of the ebola virus. Another woman is found dead with similar symptoms. Catherine and Nick investigate. Sara and Greg with help from Grissom try to determine how a the owner of a home was killed. His home was tented for infestation.

Grissom, Sofia, Sara and Greg investigate the disappearance of a woman coming home from a night out with a friend, her abandoned car found on the edge of a highway. Catherine, Warrick and Nick investigate the deaths of a hunter and his prey, a Kodiak bear.

A serial killer strikes again, and the CSI team tries new technology using evidence from a prior killing. They find a fingerprint belonging to Jesse Acheson, who becomes the prime suspect. A boy confesses to the killing of his brother, but evidence suggests that he may not have committed the crime.

Two amorous freshmen are found dead on a sleeping bag in a dorm room, and Sara and Greg run into one dead end after another as they try to determine why the students were killed. Warrick, Nick and Catherine figure out how a man is found dead in the center of a crop circle. Ecklie is called into duty for a man found dead in his car and his body later goes missing.

The CSIs investigate a man's claim that his wife fell down a set of stairs in their home.

A 28 year-old single mother is found dead. Initially, it's believed to be a suicide, but Catherine determines she was murdered. Also, Ecklie summons Grissom to refute the testimony of an entomologist in a murder trial.

The CSI team investigates the murder of a man suffering from a congenital hypertrichosis, causing him to grow excessive body hair. Elements of the case suggest a connection with a belief in werewolves. The case leads to the victim's sister, who suffers from the same disease. Because of her condition, she'd been hiding from the world, but it turns out that she's hiding facts that are vital to solving the case.

The investigation into a body found in a chimney leads the CSIs to re-open an investigation of an unsolved homicide of a female teenager named Caroline Fitzgibbons.