April's crisis of faith is challenged by a patient she treats who is a rabbi, and Meredith treats a patient who is a transplant surgeon from another hospital.

As the city of Seattle revels at the Phoenix Fair celebrating the city’s rebirth post-COVID, the Grey Sloan doctors treat a patient who encounters illegal fireworks. Meanwhile, Bailey has her sights set on hiring new doctors, but she’s having trouble finding viable options. Owen and Teddy attempt to take the next step in their engagement, and Meredith has a surprising opportunity when she meets a dynamic doctor from her mother‘s past.

The crossover starts on Station 19 S05E01 Phoenix from the Flame (I).

Meredith seeks advice from Amelia. Meanwhile, Richard is reenergized as he takes teaching to a new level at the hospital, and Winston treats a patient suffering from kidney failure.

Seattle’s favorite redhead returns and graces the Grey Sloan halls with her experience and expertise as she attempts to help Richard teach the newest crop of residents. Meanwhile, Meredith has a decision to make, and Link confides in Teddy.

Richard recruits Meredith and Bailey to help him launch a new program. Meanwhile, Addison’s patient has complications from a procedure, and Jo helps a woman who goes into premature labor.

The Grey Sloan doctors spring into action after an explosion rocks Seattle, with the incoming trauma hitting close to home. Owen experiences PTSD after he hears the explosion, while his sister Megan enlists help from Winston and Hayes in confidence. In Minnesota, Meredith and Amelia meet up with a familiar face who assists in their study.

The crossover starts on Station 19 S05E05 Things We Lost in the Fire (I).

It's Thanksgiving, and while Meredith faces travel complications due to the weather, Nick steps in to help in more ways than one; Richard and Bailey seek out emergency surgeries; Amelia and Link reconnect.

Dr. Hamilton takes his frustrations out on Meredith, so Nick gives her a chance to blow off steam by scrubbing in on a surgery. Back in Seattle, Link and Jo take their kids to a fairytale theater performance that goes wrong. Bailey and Dr. Lin attend a recruitment fair in hopes of attracting more doctors to Grey Sloan but find themselves ill-prepared.

The doctors celebrate the holidays; Hamilton and Meredith prepare for a milestone on their project; Link wants to spend the holiday with Amelia and Scout as a family; Schmitt is faced with a difficult decision during surgery.

The Grey Sloan Memorial doctors grapple with the aftermath of the car crash that involved some of their own; Meredith works to save Dr. Hamilton's life. Levi is impacted from his latest loss.

Schmitt must face the Morbidity and Mortality conference. Meanwhile, Meredith convinces Nick to scrub in on a surgery in Seattle, and Jo faces her feelings.

While Meredith, Amelia and the team prepare for Dr. Hamilton’s long-awaited, groundbreaking surgery, Bailey receives an unexpected offer. Owen’s impatience makes him a difficult physical therapy patient, forcing Link to intervene. In Minnesota, Nick makes a liver transplant a teaching moment.

Nick whisks Meredith away to his Minnesota cabin for a romantic weekend, leaving Winston and Maggie to care for Meredith’s children. Meanwhile, Amelia and Kai grow closer.

While Richard ponders his surgical abilities, Jo is charmed by her patient’s brother. Elsewhere, Megan makes sure Teddy and Owen talk out their differences, and a pet python causes an uproar.

Tensions at Grey Sloan Memorial rise as the effects of the physician shortage begin to show. Meanwhile, Meredith struggles to step away from work as she spends a sick day at home with Zola, and the hospital receives an unexpected visitor.

Bailey is on edge when an accreditation council stops by Grey Sloan to review the residency program, while Richard sets an assessment of his own for the same day. Meanwhile, Nick returns to Seattle to perform a first-of-its-kind operation with Meredith.

Bailey faces an unhappy Catherine who is facing audits for several of her Foundation hospitals. Meanwhile, Addison is back at Grey Sloan; tensions rise between Meredith and Richard, and Owen returns to work.

A former patient of Link’s, Simon, is in the ER with his pregnant wife; and Bailey receives an offer from Nick.

A dinner party is thrown at the sister house in Nick's honor. Meanwhile, Grey Sloan Memorial receives a victim of a brutal hate crime.

Due to a blood shortage, Grey Sloan Memorial is setting up a voluntary donation center. Meanwhile, Nick asks Meredith for help with his patient and Winston is hung up on his relationship with his brother.

The blood shortage at Grey Sloan Memorial continues. Meanwhile, Meredith makes a risky decision regarding a patient, and Owen’s actions to help his fellow veterans come to light.

After a long six months, Grey Sloan Memorial has reinstated its residency program. A group of talented and striving young interns has been recruited as the attending surgeons work to rebuild the program to its former glory. Meredith, still functioning as the interim chief, sees Nick for the first time since she rejected his offer to move to Minnesota. Meanwhile, Bailey tells Richard she is not ready to return to work; Levi works up the courage to break disappointing news to Jo, and things turn awkward when Link realizes he has met one of the interns already. With Amelia and Maggie’s help, the new doctors are thrown into their first day on the job dealing with injuries from a recent tornado.

The attending surgeons and interns work together to solve a medical mystery when a college kid comes in with what first looks like food poisoning but has escalating and dire complications. Meanwhile, Jo spends her day off with Bailey.

Bailey recruits the interns to create a series of social media videos informing teens about sexual health. The videos, filmed at Grey Sloan in front of a group of high schoolers, hit home as a student has medical complications during her visit. Elsewhere, Meredith and Maggie learn something new about Zola.

It’s Halloween night at Grey Sloan Memorial. Meredith and Nick try to spend some alone time together; Levi is stressed due to overworking, and Winston and Owen have the interns practice trauma training on a real cadaver.

Bailey and Addison take a road trip to volunteer at a family planning center, but a patient’s ectopic pregnancy leads to complications. Elsewhere, the interns play detective about Lucas’ relationship with Amelia, and Meredith catches up with Jackson on a trip to Boston.

On the heels of life-changing news, a thunderstorm hits Grey Sloan. The attending surgeons and interns work together to save an injured reporter and family affected by the storm. Meanwhile, a beloved author undergoes a risky surgery, and complications from the storm arise.

It’s Meredith’s last day at Grey Sloan Memorial and the doctors plan a goodbye surprise, while Nick confronts her about the future of their relationship. Elsewhere, the interns compete to scrub in on Maggie and Winston’s groundbreaking partial heart transplant procedure, and Richard asks Teddy an important question.

Addison makes a special appearance at Grey Sloan to welcome Bailey’s new OB/GYN trainees. Maggie’s lung transplant is derailed, and Nick bonds with Lucas — before the day takes a shocking turn.

In the immediate aftermath of shocking events at the clinic, the hospital goes on lockdown and the Grey Sloan doctors split up to save multiple lives; Maggie lands in hot water with Winston; Jules' roommate makes a surprise appearance.

Teddy calls an emergency meeting to discuss the intern program. Link wrestles with his own self-doubt as he preps for a massive surgery, and Nick shares some much-needed guidance with a struggling Lucas.

Richard and Teddy make an exciting announcement. Jules and Blue butt heads over Maxine’s care while Lucas helps an artist decide on a risky procedure. Jo and Mika tend to Sam as Simone faces a life-changing decision.

Simone's wedding day arrives as Jo and Link's relationship hits a major turning point.

The attending surgeons fly to Boston, forcing a reunion between Nick and Meredith. Bailey gets a big surprise.

Meredith rethinks her plans. The interns are on thin ice following a patient's death. Simone and Lucas are immediately tested in an emergency. Richard confides in Bailey. Teddy's fate is revealed.

It's all hands on deck at Grey Sloan when a group of medical students is injured by a floor collapsing at their white coat party. Jo and Link are forced to talk about the future, while Jules confronts Winston about his attitude.