Derek takes Cristina out on a fishing trip; Teddy tries to help a patient who lacks the proper insurance to seek medical treatment.

Arizona tries to reconcile with Callie, who has big news to share; Teddy faces an important decision; the residents receive new interns; the Chief makes an announcement.

Meredith, looking to prove she is Chief Resident material, learns that anything and everything can happen in an hour's time when she steps up to run the ER for a night; meanwhile, Bailey sneaks off with Eli and gets into a little mischief, and everyone is surprised when the Chief's wife, Adele, shows up as one of the ER patients.

Richard is desperate for Derek and Meredith to accept Adele into their Alzheimer's trial, but will Adele stand in her own way? Meanwhile Mark and Arizona have conflicting ideas of the kind of baby shower Callie wants, Teddy is freaked out when Henry has another health complication -- leaving them both a little exposed -- and the competitiveness amongst the residents for the Chief Resident position is amplified when Richard receives the green light for his diabetes clinical trial.

A cataclysmic event leaves the doctors shaken; Callie, on the verge of a life-changing moment, starts imagining about the hospital and her friends.

News of Meredith's dishonesty in the clinical trial comes to light, leading to unanticipated consequences for her and others; Cristina finds herself in a compromising situation, which forces her to decide between her career and her relationship; Owen posts his decision for Chief Resident, and Teddy makes a surprising choice regarding her love life -- and her future.

만화 행사장에서 사람들이 넘어져서 깔리는 대형 사고가 발생해 응급실에 부상자들이 몰려온다.

잭슨의 엄마이자 유명 비뇨기과 전문의인 캐서린 에이버리가 국내 최초로 성기 이식술을 하기 위해 병원에 온다.