The Grey Sloan doctors continue to face their new COVID-19 reality and deal with a familiar and stubborn patient. Koracick is put in charge of the interns who recently joined the hospital ranks and Link operates on a sex therapist. Elsewhere, Maggie finds comfort in Winston's virtual presence.

Bailey panics as she hears there has been a surge of COVID-19 cases, knowing she has loved ones in an assisted living facility. Meanwhile, Jackson and Richard team up against Catherine to teach her a lesson, and Teddy continues to try to mend her frayed relationships. After an intense surgery, Jo is uncertain about her future.

“Grey’s Anatomy” picks up where the previous episode of “Station 19” left off as both teams tend to a tense situation with so much at stake. Meanwhile, Jo convinces Hayes to bend the rules on a case, and Maggie and Winston reconnect.

It’s wedding day for Maggie and Winston. Meanwhile, Meredith takes on a new role at the hospital, and Jo makes a life-changing decision.

Richard recruits Meredith and Bailey to help him launch a new program. Meanwhile, Addison’s patient has complications from a procedure, and Jo helps a woman who goes into premature labor.

The doctors celebrate the holidays; Hamilton and Meredith prepare for a milestone on their project; Link wants to spend the holiday with Amelia and Scout as a family; Schmitt is faced with a difficult decision during surgery.

The Grey Sloan Memorial doctors grapple with the aftermath of the car crash that involved some of their own; Meredith works to save Dr. Hamilton's life. Levi is impacted from his latest loss.