Meredith turns heads when she shows up to work done up and ready for her blind date later that day, while Alex makes a questionable decision in order to save a patient. Meanwhile, the burden of knowing Teddy’s secret keeps Maggie up at night, ultimately making her decide she has to tell someone.

Jo becomes a safe haven volunteer and gets a call that a baby has been dropped off at Station 19. Meanwhile, Meredith moves forward with her life after facing the medical board. Jackson takes a big step in his budding romance with Vic, while Bailey and Amelia swap pregnancy updates.

Jackson creates an uncomfortable situation when he invites new girlfriend, Vic, to what he thinks is Richard and Catherine’s anniversary celebration, only to discover the dinner was called for different reasons. Elsewhere, Levi brings Nico on a trip to visit an ailing family member.

The doctors of Grey Sloan Memorial must contend with the COVID-19 pandemic; an unintentionally started fire has first responders from Station 19 bringing patients into the hospital for treatment.

The Grey Sloan doctors spring into action after an explosion rocks Seattle, with the incoming trauma hitting close to home. Owen experiences PTSD after he hears the explosion, while his sister Megan enlists help from Winston and Hayes in confidence. In Minnesota, Meredith and Amelia meet up with a familiar face who assists in their study.

The crossover starts on Station 19 S05E05 Things We Lost in the Fire (I).