Maggie gets upset when Meredith dodges her questions about DC; Bailey and Ben become concerned about Ben’s brother after he is admitted to the hospital, and Dr. Herman starts to warm up to Arizona. Meanwhile, Richard feels manipulated by Catherine.

Jackson learns about April's pregnancy, while Alex and the team of doctors handle an hours-long triple-organ transplant surgery. Meredith considers dating again, and Andrew insists on not receiving special treatment after he and Maggie go public.

Meredith and Bailey are at odds when both of their patients need a liver transplant, Owen seeks help from the other doctors when he is charged with babysitting baby Harriet for the day, and Amelia struggles with telling Owen some important news.

The hospital brings in crisis management to help them sort out allegations against Harper Avery. Nurse Olivia shows up at Grey Sloan with her son, throwing Alex and Jo for a loop Arizona decides to spend more time with Sofia who is having a hard time at school.

Meredith works on a patient who happens to specialize in matchmaking, and a seemingly drunk patient pushes Richard's buttons and gives him a medical mystery to solve. Meanwhile, Maggie tries to reach Teddy after bearing the burden of her secret becomes overwhelming as she struggles with issues in her own personal life.

Maggie treats one of Station 19’s own, and Jo learns a hard lesson. Meanwhile, when working with a family seeking asylum, Meredith makes a call that could jeopardize her career. The crossover continues on Station 19 S02E15 Always Ready (II).

After Meredith inadvertently stirs up negative press for Grey Sloan, she tries to make things right with her former colleagues, jeopardizing her community service hours. Station 19’s Ben and Vic bring a young woman into the hospital, and Jackson stands up to Koracick when he goes too far with a patient’s family. Meanwhile, Bailey receives unexpected news; and Owen finds himself at Pac-Gen North, which Alex sees as a recruiting opportunity.

Link tries to convince Amelia to take it easy during the final stage of her pregnancy. Hayes asks Meredith a surprising question, and Owen makes a shocking discovery.

The hospital ventilator shortage has the doctors gravely concerned when both a mother and daughter are in critical condition with COVID and fighting over the last ventilator. Meanwhile, Hayes’ high-risk sister-in-law with multiple sclerosis ends up in the hospital with a kidney stone, and the sister house has a few more kids join it as Amelia plays babysitter for the day.

While Meredith, Amelia and the team prepare for Dr. Hamilton’s long-awaited, groundbreaking surgery, Bailey receives an unexpected offer. Owen’s impatience makes him a difficult physical therapy patient, forcing Link to intervene. In Minnesota, Nick makes a liver transplant a teaching moment.

A bull rider shows up at Grey Sloan with severe injuries, forcing Maggie, Amelia, Owen and Blue to examine their own biases. Elsewhere, Simone can’t find anyone to be her maid of honor, and Mika takes drastic measures to pay down her student debt.

Meredith and Amelia work to secure funds for their research while Amelia finds herself at odds with a new attending. Levi runs into someone from his past, and Owen gives Winston advice. Lucas ditches Mika, forcing her to treat a patient alone.