With Finch back in the Library, Reese returns to field work, only to face his toughest case yet – protecting the privileged daughter of a Brazilian diplomat.

Finch and Reese meet their match: a tech billionaire whose curiosity and endless resources could expose their identities and ruin their efforts to save his life.

The team must figure out if a prominent lawyer orchestrated the murder of her husband or if she is being framed; Carter is spotted with Reese by her new partner.

Reese boards an international flight in an attempt to put the team and the past behind him, but is angered when he realizes his travel plans have been manipulated.

Reese and Shaw pose as alumni at a high school reunion in order to keep eyes on the latest POI. Meanwhile, Finch and Fusco travel to Washington, D.C., to investigate the motivations behind Vigilance’s latest attack.

Despite not wanting to help with the new numbers, Finch's interest is piqued when the newest person of interest turns out to be a brilliant college student involved with a mysterious scavenger hunt.

Reese finds himself on a dangerous personal journey when he takes on a homicide case Detective Carter was never able to close.

The Machine sends Reese and Finch to a wedding to protect a pair of POIs before their nuptials. Also, Fusco becomes angry at being kept in the dark by the team and takes it upon himself to investigate a string of missing person reports.

Finch’s number comes up when a fatal error blows his cover identity and sets off a deadly series of escalating encounters with Samaritan’s operatives.