Alma asks Hickok to investigate the tragic fallout of her husband's gold claim purchase. McCall plots revenge after being humiliated at poker. Charlie Utter departs camp for Cheyenne. Doc Cochran makes a house call to the Bella Union.

A much-needed vaccine arrives in Deadwood. There are rumblings of a treaty with the Sioux. Swearengen is reluctant to accept advice from Farnum while Trixie is away. Alma reconsiders her plans for her gold claim. Stubbs learns an important lesson from Tolliver.

Swearengen's deteriorating health worries his employees. Alma ponders a real-estate move after surveying her operation. A mining-company agent makes his presence known. Maddie lets Joanie in on a secret about their first client.

Wolcott draws Utter's ire during the questioning of a suspect. Merrick is overzealous in re-establishing his newspaper. Fields and Hostetler have little luck with a wild horse. Swearengen alters his agreement with Miss Isringhausen.