Dexter shows up at his 20th high-school reunion with the intention of confronting the former prom king. Elsewhere, an investigation into a heinous murder with religious overtones leads Dexter to ponder spiritual matters and wonder about his son's legacy. And an unexpected situation results in Debra becoming a hero.

Brother Sam, a minister with a criminal history, is brought in by the homicide department to help solve a macabre murder, but Dexter sees him for what he really is, and it's definitely not a man of God. Elsewhere, Debra's sudden hero status elicits a pair of surprising proposals.

Dexter is confronted with a sobering glimpse of his own potential future when a serial killer from his past makes a startling reappearance; Debra is uncomfortable in her new job; Travis struggles to keep his mentor happy, as he and Gellar prepare a new twisted tableau, ensuring Debra's next task will be a daunting one.

Much to his own surprise, an emergency with Harrison and a new tableau from Gellar and Travis has Dexter leaning on Brother Sam and an unexpected winged messenger for support as he questions the idea of faith; with proof of a religiously motivated killer, Homicide hunts for a zealot, with Debra giving her first official press conference.

Dexter finds himself teamed up with a fellow Dark Passenger when he takes a road trip to Nebraska to tie up some loose ends from the past; Debra deals with the complications of her promotion as she leads the Doomsday investigation.

Dexter uses lessons he learned from Brother Sam to follow up on some new leads in the Doomsday investigation; Debra butts heads with Captain LaGuerta over the case of a dead call girl.

Dexter receives help from an unexpected source while hunting the Doomsday Killers and staying one step ahead of Homicide; Debra discovers something new about herself in therapy.

In the Season 6 finale, Dexter and Homicide race against a lunar eclipse to catch the Doomsday Killers before their final gruesome act; Debra struggles with a new emotional reality.

After witnessing her brother kill Travis Marshall, Debra attempts to reconcile with Dexter while struggling to cover up their involvement with the murder. Meanwhile, Detective Mike Anderson has an unfortunate run-in, Quinn and Batista begin to make amends, and LaGuerta finds evidence that causes her to re-think the closed Bay Harbor Butcher case.

Miami Metro sets out to unearth new evidence on a claim from a local convict that he has new information regarding a 15-year-old crime spree; Debra tries to cure Dexter of his killer tendencies.

Fresh out of jail, Isaak renews his pursuit of Dexter while Quinn continues his power struggle with the Koshkas. Dexter tries to keep Debra in the dark about his relationship with Hannah, but a surprise visit from Astor, Cody and Harrison throws a wrench into his plans.

It's Christmas time, and Debra learns it may be better to receive when she gets a tip from Hannah's father... one that could lead to incriminating Dexter in a crime. Meanwhile, Dexter discovers that the man behind his mother's death has been released from prison.