Coulson's team is up against the beautiful and deadly Bobbi Morse--Security Chief for HYDRA. Meanwhile, Skye's father forces Raina to reunite him with his daughter at any cost.

Coulson and team find themselves in an epic face-off against HYDRA to uncover an ancient secret, while Ward kidnaps his brother, Senator Christian Ward, for a violent trip down memory lane.

Coulson and Whitehall's forces meet in an explosive confrontation that dramatically alters everyone's fates. Meanwhile, Skye discovers shocking secrets about her past.

Coulson's team must deal with the consequences of their war with HYDRA as shocking revelations threaten to tear them apart, and HYDRA makes a dangerous move that may involve a traitor in S.H.I.E.L.D.'s midst.

Cal seeks revenge on Coulson by assembling a team of Super Villains to destroy S.H.I.E.L.D. Meanwhile, May calls on renowned Dr. Andrew Garner, her charismatic ex-husband, with a crisis that threatens to tear the team apart.