Coulson and his team are now wanted fugitives with limited resources, but that's not stopping them from keeping the world safe from powerful and unseen threats everywhere. However, with new members they hardly know, will S.H.I.E.L.D. ever be trusted again?

Hunted and running out of solutions, Phil Coulson puts his team right in the line of fire in the hopes of saving them all. But with General Glenn Talbot, HYDRA, and Carl Creel all on the attack, can they possibly survive? Meanwhile, a mysterious Doctor harbors some dangerous secrets that could destroy one of our core team members.

Coulson and his team race against HYDRA to get to Donnie Gill--a dangerous gifted with the ability to freeze objects--while Simmons is caught in the crossfire.

While on a mission to learn more about the secrets of the mysterious writing, Coulson finds himself attacked by the only person he can trust: Agent Melinda May. Meanwhile, the rest of the team is trapped in an explosive situation, and it's up to Fitz to save them--but is he up to it?

Coulson's team is up against the beautiful and deadly Bobbi Morse--Security Chief for HYDRA. Meanwhile, Skye's father forces Raina to reunite him with his daughter at any cost.

The team discovers murder victims with the alien glyphs on them that Coulson's been etching. All of Coulson's secrets and lies come to a head.

Coulson and team find themselves in an epic face-off against HYDRA to uncover an ancient secret, while Ward kidnaps his brother, Senator Christian Ward, for a violent trip down memory lane.

Coulson's team must deal with the consequences of their war with HYDRA as shocking revelations threaten to tear them apart, and HYDRA makes a dangerous move that may involve a traitor in S.H.I.E.L.D.'s midst.

Coulson and his team are still reeling from a shocking revelation that leaves the team fractured as they must decide what to do with one of their own. Meanwhile, Bobbi and Mack reveal their true allegiance to Hunter, while elsewhere, Ward and Agent 33 embark on a personal mission.

Daisy finds herself teamed up with an unlikely partner. Meanwhile, Aida prepares to put her ultimate end game into effect.