Joanna becomes over involved with a patient and soon regrets her actions. Alice and Nikki wait to see if their transplant has been successful and old flames reignite between David and Patricia

David's affair with Patricia begins to affect his work at The Beeches. Andrew doesn't understand what is wrong with him but Joanna is well aware of the fact he is cheating on Claire. Elsewhere Claire begins to have her own suspicions about her husband when he fails to attend a family emergency whilst on call.

Dr Sam Morgan arrives in Cardale as David's locum. He is thrown straight into the deep end when he has to tell a pregnant patient she has cervical cancer. Joanna has dinner with old flame Martin Henderson and gets a lot more then she bargained for when it is clear he is still in love with her. Meanwhile the romantic tension between Andrew and Dawn is brought to the fore.

Joanna is caught up in a dangerous situation when she visits a patient who is on the run. Sam is still grieving over the death of Alison but Andrew has some news that will brighten his day. Meanwhile Andrew and Dawn finally give into their feelings.

A meningitis outbreak throws Cardale into chaos. Andrew, Erica and David work around the clock trying to avoid further cases of the disease and convince the health authority that all the children need to be vaccinated. Meanwhile Andrew and Erica discuss their relationship

Andrew arrives back in Liverpool and is meeting fierce objection from his mother over his treatment of her. Erica is involved in a highly sensitive child abuse case that splits Cardale in half. Joanne takes her authority at the surgery too far and locum Nick Goodson arrives......

Back from Liverpool Andrew is ready to look to his future with Erica but questions arise over her commitment to him. The situation is not helped by Nick's intervention. Meanwhile David is concerned when Claire's behaviour begins top spiral out of control – is she getting sick again?

The Beeches staff are slowly alerted to Nicks' web of deceit. It appears his stories and his actions have fooled them all. Back in Liverpool it's a sad day for the Attwoods when Rose passes away.

When the new doctor from The Health Centre takes a shine to Andrew, Erica realise her true feelings for him. It's time for her to bite the bullet and let him know how she feels. How will he react?

Sparks fly between Erica and David when clash over a surrogate case. But is there more to their disagreement then meets the eye? Meanwhile Alice gets the whole of Cardale involved in her campaign to stop a new supermarket being built.

Cardale prepares for the wedding of Andrew and Erica but a long line of disasters provides them with the perfect pre wedding initiation test. The pop band turns into a group of line dancers, the caterers pull out and the grooms suit doesn't fit, but surely the most pressing issue is the last minute doubts looming over the bride.......

Cardale is shaken by the news of David's death. Andrew and Dawn rally round a devastated Claire whilst Joanna tries to hold the surgery together. As the funeral arrangements are underway Claire learns of David's affair and comes face to face with Patricia.

Claire arrives back in Cardale and announces she is selling David's share of The Beeches. As David owned the larger share, The Beeches looks set to fold unless Andrew can convince Joanna to become a full partner in the practice.......