As the 4400 become even more disenchanted with their accommodations, new rules have everyone on edge. Andre and LaDonna help Claudette push her newfound ability to new limits. Shanice gets an unexpected visitor.

LaDonna signs up for 15 more minutes of fame but quickly realizes she doesn't have the clout she once had. Jharrell picks an inopportune time to speak his truth, and it may cost him dearly. Andre is eager to get back to medicine.

Finally there is some good news for a few of the 4400. Andre looks to study some of his new friends but mistakes from his past begin to affect him in present day. Rev finds some information about his son.

Keisha hears the truth about the day she lost her sister, moving her to take a chance. Shanice and Andre enjoy a day out. Hayden and Mariah grow closer.