APTN National News is the Canadian national news program aired by the Aboriginal Peoples Television Network. It is broadcast from Winnipeg, Manitoba, Canada.

The program formerly aired in two daily editions: APTN National News Daytime aired at 12:30 p.m., and APTN National News Primetime aired at 6:30 p.m. The program now produces only a single full edition each day, which airs at 6 and 11:30 p.m. Eastern Time nightly with short headline news updates at the top of the hour during the afternoon. The program's current anchors are Michael Hutchinson and Cheryl McKenzie.

In September 2009, two current affairs shows, APTN InFocus and APTN Investigates launched.

In addition to its main newsroom in Winnipeg, APTN National News has news bureaus in Halifax, Montreal, Ottawa, Toronto, Saskatoon, Edmonton, Vancouver, Iqaluit, Yellowknife and Whitehorse.

News and current affairs staff at APTN applied for and received union certification with the Canadian Media Guild from the Canadian Labour Board in 2002. Unionized staff reached its first collective agreement with APTN management in April 2003.

On June 8, 2012, award-winning journalist Karyn Pugliese was appointed as the director of news and current affairs for APTN. Pugliese previously worked as the Ottawa correspondent for APTN National News from 2000 to 2006.