The discovery of a dead former MI6 agent uncovers secrets from Tennant’s past, forcing her to go to extreme lengths to track down the responsible party.

When a figure from Tennant’s CIA past re-emerges, the NCIS team seeks help from the most unlikely place to catch a killer who threatens to destroy everything Tennant has built.

Following the crash of a prisoner transport plane, the NCIS team must find the convicts that escaped onto the island. Meanwhile, Sam Hanna and Tennant are tasked with locating a high-profile Russian prisoner known as "The Chemist".

When a high-value bioweapons expert is murdered in a secure facility on Hawai'i, NCIS and the NCIS Elite team join forces to track down the killer and discover an even deadlier threat.

Following a devastating ambush with a deadly bioweapon, the NCIS team must track down a mysterious terrorist group before they can strike again.